Top Definition
A cocktail, that is either Snorted or Injected, made of Cocaine and Methamphetamine, instead of Cocaine and Heroine.

Named for the fact that Wyoming is statistically known for its Methamphetamine use.
They got jacked up on Wyoming Speedballs and fucked like rabbits for days!
dari WyomingGurl Rabu, 22 September 2010

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