A very new sleep medication, rozerem is based on the over the counter melatonin supplement (and melatonin receptor in the brain). Apparently highly effective at targeting circadian rhythm "issues," and inducing a quick sleep rather than similar meds like ambien which focus on anxiety-related insomnia (and thus, also help the patient sleep longer through the night), rozerem does not chemically relate to ambien, lunesta, or sonata, which, like their benzo cousins, can be high-inducing and mentally and physically addictive. Thus, rozerem is not YET even a controlled substance (apparently tests have shown that the likelihood of addiction is extremely low), and the only "side effects" are (if the drug works with efficacy) sedation. However, it will soon be noted in the psychiatric and pharmacologic worlds that rozerem, like some of the aforementioned medications, indeed DOES induce a weed-like wonderful high, and has, therefore, the propensity for dependence and/or abuse. These effects include lack of coordination, slight memory loss, mild euphoria, mild disinhibition, as well as LIGHT sedation (especially if taken during the day after a full night's sleep). The usual dosing is in 8 mg tablets, but people seeking "rozerem highs" might take as much as a total of 24-32 mg at a time, mix it with booze or other anti-anxiety benzos or sleep aids (such as ambien). While this high lasts only about an hour at maximum, the sedating effect, while unnoticed in the abusing patient, is indeed still in one's system, and rozerem-poppers have been known to abuse the pill during the day, get high, feel "normal," lay off for the rest of the day, and then sleep for as much as 30 hours straight.
Richard was exhausted and popped 16 mg of rozerem expecting to feel just a little sleepy or groggy or to not feel anything at all. Within 15 minutes, however, Richard was high as a kite, almost slurring his speech and staggering like a drunk. Elated from the high, Richard was wired for the remainder of the evening, and then went to sleep for over 16 hours, uninterrupted.
dari Arieh Jum'at, 18 Agustus 2006